Title : Effect of metformin compared with hypocaloric diet on serum C-reactive protein level and insulin resistance in obese and overweight women with polycystic ovary syndrome.

Pub. Date : 2013 Apr

PMID : 23279603






5 Functional Relationships(s)
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1 Effect of metformin compared with hypocaloric diet on serum C-reactive protein level and insulin resistance in obese and overweight women with polycystic ovary syndrome. Metformin C-reactive protein Homo sapiens
2 AIM: The aim of the present study was to investigate the efficacy of Metformin compared with a hypocaloric diet on C-reactive protein (CRP) level and markers of insulin resistance in obese and overweight women with polycystic ovary syndrome (PCOS). Metformin C-reactive protein Homo sapiens
3 AIM: The aim of the present study was to investigate the efficacy of Metformin compared with a hypocaloric diet on C-reactive protein (CRP) level and markers of insulin resistance in obese and overweight women with polycystic ovary syndrome (PCOS). Metformin C-reactive protein Homo sapiens
4 Serum concentration of hs-CRP significantly decreased in both the Metformin (5.29 +- 2.50 vs 3.81 +- 1.99, P = 0.008) and diet groups (6.08 +- 2.14 vs 4.27 +- 1.60, P = 0.004). Metformin C-reactive protein Homo sapiens
5 CONCLUSIONS: Although weight reduction has equal efficacy with Metformin in decreasing serum hs-CRP levels, it was significantly more effective in improving insulin resistance in obese and overweight PCOS women. Metformin C-reactive protein Homo sapiens