Pub. Date : 2013 Feb 22
PMID : 23275337
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we demonstrate that incubation (2 h) of murine islets or Min6 beta cell line with the SSRIs paroxetine, fluoxetine, or sertraline inhibited insulin-induced Tyr phosphorylation of insulin receptor substrate (IRS)-2 protein and the activation of its downstream targets Akt and the ribosomal protein S6 kinase-1 (S6K1). | Paroxetine | thymoma viral proto-oncogene 1 | Mus musculus |