Title : Effect of tumor suppressor PTEN gene on apoptosis and cell cycle of human airway smooth muscle cells.

Pub. Date : 2013 Mar

PMID : 23275086






2 Functional Relationships(s)
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1 We hypotheses that PTEN gene could affect the growth and viability of ASMCs through the regulation of PI3K/Akt, MAPK, and cell cycle-related gene expression. asmcs phosphatase and tensin homolog Homo sapiens
2 Moreover, overexpression of PTEN could induce ASMCs arrested in the G0/G1 phase through the downregulation of Cyclin D1 and upregulation of p21 expressions. asmcs phosphatase and tensin homolog Homo sapiens