Pub. Date : 2013 Feb 1
PMID : 23273608
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors. | huperzine A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Four series of novel heterodimers comprised of donepezil and huperzine A (HupA) fragments were designed, synthesized, and evaluated in search of potent acetylcholinesterase (AChE) inhibitors as potential therapeutic treatment for Alzheimer"s disease. | huperzine A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | Four series of novel heterodimers comprised of donepezil and huperzine A (HupA) fragments were designed, synthesized, and evaluated in search of potent acetylcholinesterase (AChE) inhibitors as potential therapeutic treatment for Alzheimer"s disease. | huperzine A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | Heterodimers comprised of dimethoxyindanone (from donepezil), hupyridone (from HupA), and connected with a multimethylene linker, were identified as potent and selective inhibitors of AChE. | huperzine A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |