Title : Epithelial calcium-sensing receptor activation by eosinophil granule protein analog stimulates collagen matrix contraction.

Pub. Date : 2013 Apr

PMID : 23269116






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 HEK-CaSR stimulation with PA or Ca(2+) resulted in greater pERK activation than that of stimulated HEK-WT cells. polyarginine calcium sensing receptor Homo sapiens
2 PA stimulated greater HEK-CaSR lattice contraction than unstimulated lattices. polyarginine calcium sensing receptor Homo sapiens
3 CONCLUSION: Exposure of intestinal epithelia to the EDGP analog PA stimulates CaSR-dependent ERK phosphorylation and epithelial-mediated collagen lattice contraction. polyarginine calcium sensing receptor Homo sapiens