Pub. Date : 2012 Dec
PMID : 23268412
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rosiglitazone treatments significantly lowered the contents of total cholesterol and free cholesterol (P<0.05), decreased the expression of ACAT-1 (P<0.05), and increased SR-BI expression (P<0.05) in the foam cells in a dose-dependent manner. | Rosiglitazone | acetyl-Coenzyme A acetyltransferase 1 | Mus musculus |
| 2 | CONCLUSION: Rosiglitazone can decrease the contents of total and free cholesterol, down-regulate ACAT-1 expression and up-regulate SR-BI expression in the foam cells produce the anti-atherosclerotic effect. | Rosiglitazone | acetyl-Coenzyme A acetyltransferase 1 | Mus musculus |