Pub. Date : 2013 Feb 25
PMID : 23261716
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When NADPH was used, as compared to NADH, the reductions of CBCP-one by AKR1C1, AKR1C2 and AKR1C3 were 14-, 51- and 31-fold more efficient, respectively. | NADP | aldo-keto reductase family 1 member C2 | Homo sapiens |
| 2 | This NADPH-dependent reduction of CBCP-one was then used to re-evaluate inhibitory potencies of the known inhibitors of the target AKR1C3 and the anti-target AKR1C2, medroxyprogesterone acetate and ursodeoxycholic acid, respectively, showing Ki constants similar to the reported values. | NADP | aldo-keto reductase family 1 member C2 | Homo sapiens |