Title : Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages.

Pub. Date : 2013 Apr

PMID : 23258232






1 Functional Relationships(s)
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1 Bleomycin-treated Pirb(-/-) mice displayed increased lung histopathology and an increased expression of collagen and of the IL-4-associated profibrogenic markers Relm-alpha, MMP-12, TIMP-1, and osteopontin, which were localized to alveolar macrophages. Bleomycin tissue inhibitor of metalloproteinase 1 Mus musculus