Title : Endothelial nitric-oxide synthase activation generates an inducible nitric-oxide synthase-like output of nitric oxide in inflamed endothelium.

Pub. Date : 2013 Feb 8

PMID : 23255592






1 Functional Relationships(s)
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1 In inflamed HLMVEC (pretreated with interleukin-1beta and interferon-gamma), we found enhanced binding of eNOS to calcium-calmodulin at basal Ca(2+) levels, thereby increasing its basal activity that was dependent on extracellular l-Arg. Arginine nitric oxide synthase 3 Homo sapiens