Title : The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance.

Pub. Date : 2013 Feb

PMID : 23254431






1 Functional Relationships(s)
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1 To better understand the evolution of these proteins under selective pressure, we exposed a Saccharomyces cerevisiae yeast strain already overexpressing Pdr5 to a lethal concentration of cycloheximide. Cycloheximide ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C