Pub. Date : 1990 Mar
PMID : 2325409
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Testosterone oxidation by microsomal cytochromes P-450a, P-450b, P-450h and P-450p was also differentially affected by pH (over the range 6.8-8.0). | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 2 | The decline in testosterone oxidation by cytochromes P-450a, P-450b and P-450h that accompanied an increase in ionic strength or pH could be duplicated in reconstitution systems containing purified P-450a, P-450b or P-450h, equimolar amounts of NADPH-cytochrome P-450 reductase and optimal amounts of dilauroylphosphatidylcholine. | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 3 | The decline in testosterone oxidation by cytochromes P-450a, P-450b and P-450h that accompanied an increase in ionic strength or pH could be duplicated in reconstitution systems containing purified P-450a, P-450b or P-450h, equimolar amounts of NADPH-cytochrome P-450 reductase and optimal amounts of dilauroylphosphatidylcholine. | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 4 | This result indicated that the decline in testosterone oxidation by cytochromes P-450a, P-450b and P-450h was a direct effect of ionic strength and pH on these enzymes, rather than a secondary effect related to the increase in testosterone oxidation by cytochrome P-450p. | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 5 | This result indicated that the decline in testosterone oxidation by cytochromes P-450a, P-450b and P-450h was a direct effect of ionic strength and pH on these enzymes, rather than a secondary effect related to the increase in testosterone oxidation by cytochrome P-450p. | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |