Title : Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy.

Pub. Date : 2013 Jan

PMID : 23252947






1 Functional Relationships(s)
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1 MATERIALS & METHODS: Twenty-five SNPs within seven CBZ pathway genes, namely CYP3A4, CYP3A5, EPHX1, NR1I2, UGT2B7, ABCB1 and ABCC2, were analyzed for association with CBZ pharmacokinetics in 90 epilepsy patients. Carbamazepine cytochrome P450 family 3 subfamily A member 5 Homo sapiens