Pub. Date : 2012
PMID : 23251812
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Octanoylated Ghrelin Inhibits the Activation of the Palmitic Acid-Induced TLR4/NF-kappaB Signaling Pathway in THP-1 Macrophages. | Palmitic Acid | toll like receptor 4 | Homo sapiens |
| 2 | To investigate the effect of acylated ghrelin on the activation of TLR4/NF-kappaB signaling pathway induced by palmitic acid in human monocyte-derived (THP-1) macrophages, THP-1 macrophages were cultured for 12 h by palmitic acid with various concentrations. | Palmitic Acid | toll like receptor 4 | Homo sapiens |
| 3 | Compared to the THP-1 macrophages without palmitic acid, the level of TLR4 mRNA protein and NF-kappaB p65 phosphorylation and the expression of TNF-alpha and IL-1beta increased after treatment by palmitic acid in a dose-dependent fashion (P < 0.05). | Palmitic Acid | toll like receptor 4 | Homo sapiens |