Pub. Date : 2012
PMID : 23243430
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The results showed that Sal B and perindopril inhibited rat hepatic fibrosis and reduced expression of Ang II receptor type 1 (AT1R) and ERK activation in fibrotic liver. | salvianolic acid B | Eph receptor B1 | Rattus norvegicus |
2 | Sal B and losartan also inhibited Ang II-stimulated HSC activation including cell proliferation and expression of type I collagen I (Col-I) and alpha-smooth muscle actin (alpha-SMA) production in vitro, reduced the gene expression of transforming growth factor beta (TGF-beta), and downregulated AT1R expression and ERK and c-Jun phosphorylation. | salvianolic acid B | Eph receptor B1 | Rattus norvegicus |