Title : β-elemene inhibits the proliferation of T24 bladder carcinoma cells through upregulation of the expression of Smad4.

Pub. Date : 2013 Feb

PMID : 23228961






4 Functional Relationships(s)
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1 beta-elemene inhibits the proliferation of T24 bladder carcinoma cells through upregulation of the expression of Smad4. beta-elemene SMAD family member 4 Homo sapiens
2 The aim of this study was to investigate whether beta-elemene is able to repress the proliferation of T24 bladder carcinoma cells through regulation of the expression of the tumor suppressor gene, Smad4. beta-elemene SMAD family member 4 Homo sapiens
3 Western blot and RT-PCR analyses revealed that the expression of the Smad4 protein and mRNA was upregulated by treatment with beta-elemene. beta-elemene SMAD family member 4 Homo sapiens
4 Our results revealed that beta-elemene was able to upregulate the expression of Smad4 in tumor cells to inhibit the proliferation of these cells. beta-elemene SMAD family member 4 Homo sapiens