Title : Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.

Pub. Date : 2013 Feb 1

PMID : 23228697






1 Functional Relationships(s)
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1 Inhibition of this carboxylesterase probably presents a major source for altered therapeutic activity of these medicines if co-administered with orlistat. Orlistat carboxylesterase 1 Homo sapiens