Pub. Date : 2013 Mar
PMID : 23228564
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FK506 and rapamycin reduced the association between TRPC1 and Orai1 with FK506 binding protein (52) (FKBP52) in human platelets, and between TRPC1 and the type II IP(3)R, which association is known to be crucial for the maintenance of SOCE in human platelets. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |
| 2 | Finally, in MEG 01 incubated with FK506 we observed a reduction in TRPC1/FKBP52 coupling, and similarly, FKBP52 silencing reduced the association between IP3R type II and TRPC1 during SOCE. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |
| 3 | Finally, in MEG 01 incubated with FK506 we observed a reduction in TRPC1/FKBP52 coupling, and similarly, FKBP52 silencing reduced the association between IP3R type II and TRPC1 during SOCE. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |