Pub. Date : 2013 Feb
PMID : 23202364
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We previously showed that mature heart valves calcify in response to retinoic acid (RA) treatment through downregulation of the SRY transcription factor Sox9. | Tretinoin | SRY (sex determining region Y)-box 9 | Mus musculus |
| 2 | We previously showed that mature heart valves calcify in response to retinoic acid (RA) treatment through downregulation of the SRY transcription factor Sox9. | Tretinoin | SRY (sex determining region Y)-box 9 | Mus musculus |
| 3 | Using a pharmacological approach, we show that RA-mediated Sox9 repression and calcification is regulated by classical RA signaling and requires both RA and retinoid X receptors. | Tretinoin | SRY (sex determining region Y)-box 9 | Mus musculus |