Title : Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling.

Pub. Date : 2012

PMID : 23199229






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1 BACKGROUND: Glucocorticoids, such as prednisolone, are widely used anti-inflammatory drugs, but therapy is hampered by a broad range of metabolic side effects including skeletal muscle wasting and insulin resistance. Prednisolone insulin Homo sapiens
2 Finally, urinary levels of proteinogenic amino acids at day 1 and of N-methylnicotinamide at day 15 significantly correlated with the homeostatic model assessment of insulin resistance and might represent biomarkers for prednisolone-induced insulin resistance. Prednisolone insulin Homo sapiens
3 Finally, urinary levels of proteinogenic amino acids at day 1 and of N-methylnicotinamide at day 15 significantly correlated with the homeostatic model assessment of insulin resistance and might represent biomarkers for prednisolone-induced insulin resistance. Prednisolone insulin Homo sapiens