Title : Bisphenol A inhibits voltage-activated Ca(2+) channels in vitro: mechanisms and structural requirements.

Pub. Date : 2013 Feb

PMID : 23197648






1 Functional Relationships(s)
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1 Macroscopic Ba(2+) / Ca(2+) currents through native L-, N-, P/Q-, T-type Ca(2+) channels in rat endocrine GH(3) cells, mouse dorsal root ganglion neurons or cardiac myocytes, and recombinant human R-type Ca(2+) channels expressed in human embryonic kidney (HEK) 293 cells were rapidly and reversibly inhibited by BPA with similar potency (EC(50) values: 26-35 muM). Barium latexin Homo sapiens