Title : Vitamin D analogs decrease in vitro secretion of RANTES and enhance the effect of budesonide.

Pub. Date : 2012

PMID : 23183768






2 Functional Relationships(s)
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1 Budesonide and calcitriol administered in 1:3 ratio and budesonide and tacalcitol in 1:1 and 1:3 reduced RANTES concentration significantly better than each of the drug used in monotherapy (p<0.05). Budesonide C-C motif chemokine ligand 5 Homo sapiens
2 Budesonide and tacalcitol in 1:1 and 1:3 ratios suppressed RANTES production to the lowest level (171.8+-97.6pg/ml and 178.7+-105.22pg/ml, respectively). Budesonide C-C motif chemokine ligand 5 Homo sapiens