Title : Role of ABC transporters in the pathogenesis of Alzheimer's disease.

Pub. Date : 2012 Nov 21

PMID : 23181169






1 Functional Relationships(s)
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1 Recent studies have unraveled important roles of ABC transporters including ABCB1 (P-glycoprotein, P-gp), ABCG2 (breast cancer resistant protein, BCRP), ABCC1 (multidrug resistance protein 1, MRP1), and the cholesterol transporter ABCA1 in the pathogenesis of AD and Abeta peptides deposition inside the brain. Cholesterol ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens