Pub. Date : 2010 Dec
PMID : 23181152
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The ocular cancer, retinoblastoma cells were treated with fatty acid synthase (FASN) enzyme inhibitors: cerulenin, triclosan and orlistat. | Cerulenin | fatty acid synthase | Homo sapiens |
2 | The ocular cancer, retinoblastoma cells were treated with fatty acid synthase (FASN) enzyme inhibitors: cerulenin, triclosan and orlistat. | Cerulenin | fatty acid synthase | Homo sapiens |
3 | The crystal structures of ketoacyl synthase (PDB ID:3HHD) (cerulenin) and thioesterase (PDB ID:2PX6) (orlistat) domains of human FASN were utilized for docking, while for the non-crystallised human FASN enoyl reductase domain (triclosan), homology model was built and used for docking. | Cerulenin | fatty acid synthase | Homo sapiens |