Title : Clinical evidence of pharmacokinetic changes in thalidomide therapy.

Pub. Date : 2013

PMID : 23165864






2 Functional Relationships(s)
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1 Genetic factors including single nucleotide polymorphisms (SNPs) that change cytochrome P450 (CYP) activity and epigenetic regulation that modifies CYP expression levels may contribute to the changes in pharmacokinetics and adverse drug reactions (ADRs) of thalidomide. Thalidomide cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Genetic factors including single nucleotide polymorphisms (SNPs) that change cytochrome P450 (CYP) activity and epigenetic regulation that modifies CYP expression levels may contribute to the changes in pharmacokinetics and adverse drug reactions (ADRs) of thalidomide. Thalidomide cytochrome P450 family 4 subfamily F member 3 Homo sapiens