Title : Phenobarbital pretreatment alters the localization of CCl4-induced changes in rat liver microsomal fatty acids.

Pub. Date : 1990 Mar 15

PMID : 2315927






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Phenobarbital pretreatment alters the localization of CCl4-induced changes in rat liver microsomal fatty acids. Phenobarbital C-C motif chemokine ligand 4 Rattus norvegicus
2 Phenobarbital treatment induces an isozyme(s) of liver microsomal cytochrome P450 susceptible to CCl4 and enhances the latter"s lethality. Phenobarbital C-C motif chemokine ligand 4 Rattus norvegicus
3 Phenobarbital pretreatment accelerated the CCl4-induced formation of diene conjugates in the microsomal lipids. Phenobarbital C-C motif chemokine ligand 4 Rattus norvegicus
4 These data demonstrate that phenobarbital pretreatment is associated with a shift in the predominant phospholipid locus from phosphatidylserine to phosphatidylethanolamine for the early CCl4-induced fatty acid changes in rat liver microsomes. Phenobarbital C-C motif chemokine ligand 4 Rattus norvegicus