Title : Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells.

Pub. Date : 2012 Nov 15

PMID : 23153039






2 Functional Relationships(s)
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1 Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells. Reactive Oxygen Species vascular cell adhesion molecule 1 Homo sapiens
2 CONCLUSIONS: In HRMCs, LPS-induced VCAM-1 expression was, at least in part, mediated through a TLR4/MyD88/ c-Src/NADPH oxidase/ROS/p38 MAPK-dependent p300 and ATF2 pathway associated with recruitment of monocyte adhesion to kidney. Reactive Oxygen Species vascular cell adhesion molecule 1 Homo sapiens