Title : Nicotine induces the expression of C-reactive protein via MAPK-dependent signal pathway in U937 macrophages.

Pub. Date : 2012 Nov

PMID : 23149874






1 Functional Relationships(s)
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1 These demonstrate that nicotine has ability to induce CRP expression in macrophages through nAChR-ERK1/2/p38 MAPK-NF-kappaB signal pathway, which contributes to better understanding of the pro-inflammatory and pro-atherosclerotic effects of nicotine in cigarette smokers. Nicotine mitogen-activated protein kinase 3 Homo sapiens