Title : Alpha-tocopheryl polyethylene glycol succinate-emulsified poly(lactic-co-glycolic acid) nanoparticles for reversal of multidrug resistance in vitro.

Pub. Date : 2012 Dec 14

PMID : 23149859






1 Functional Relationships(s)
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Protein Name
Organism
1 After SN-38 was released from TPGS/PLGA/SN-38 NPs in MDR cells, TPGS or/and PLGA may modulate the efflux microenvironment of the P-gp pump, such as mitochondria and the P-gp domain with an ATP-binding site. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens