Pub. Date : 2013 Feb
PMID : 23142498
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NF-kappaB pathway mediates vascular smooth muscle response to nicotine. | Nicotine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Nicotine-induced effects were observed in SMCs by both monoculture and co-culture with the 3 mum-pore size, including the phosphorylation of IKK and IkappaB, the shift of transcription factor NF-kappaB, and the enhancement of SMC cytoskeleton protein expression and migration ability, but none were observed by co-culture with the 0.4 mum-pore size. | Nicotine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | The results imply that nicotine induces SMC cytoskeleton protein up-expression and migration via the NF-kappaB signaling pathway and that EC-SMC crosstalk via CAM facilitates its response to nicotine. | Nicotine | nuclear factor kappa B subunit 1 | Homo sapiens |