Title : Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac.

Pub. Date : 2012 Dec 28

PMID : 23139415






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We identified an Epac1 inhibitor compound named CE3F4 that blocked Epac1 guanine nucleotide exchange activity toward its effector Rap1 both in cell-free systems and in intact cells. Guanine Nucleotides Rap guanine nucleotide exchange factor 3 Homo sapiens
2 We identified an Epac1 inhibitor compound named CE3F4 that blocked Epac1 guanine nucleotide exchange activity toward its effector Rap1 both in cell-free systems and in intact cells. Guanine Nucleotides Rap guanine nucleotide exchange factor 3 Homo sapiens