Title : Involvement of peripheral cannabinoid and opioid receptors in β-caryophyllene-induced antinociception.

Pub. Date : 2013 May

PMID : 23138934






2 Functional Relationships(s)
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1 The antinociceptive effect produced by BCP was prevented by pretreatment with AM630, a selective CB2 receptor antagonist, but not by AM251, a selective CB1 receptor antagonist. caryophyllene cannabinoid receptor 2 (macrophage) Mus musculus
2 BCP is mediated by activation of CB2 receptors, which stimulates the local release from keratinocytes of the endogenous opioid beta-endorphin. caryophyllene cannabinoid receptor 2 (macrophage) Mus musculus