Pub. Date : 2012 Dec
PMID : 23134893
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | beta-Carotene 15,15"-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 2 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 3 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 4 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 5 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 6 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 7 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 8 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 9 | Use of genetic variation in beta-carotene 15,15"-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids unconfounded by other carotenoid-containing food constituents, but important variants must be identified. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 10 | OBJECTIVE: Our goal was to select BCMO1 single nucleotide polymorphisms (SNPs) that predict plasma carotenoid concentrations for use in future epidemiologic studies. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 11 | DESIGN: We assessed the associations between 224 SNPs in BCMO1 +- 20 kb imputed from the 1000 Genomes Project EUR reference panel with plasma carotenoid and retinol concentrations by using 7 case-control data sets (n = 2344) within the Nurses" Health Study, randomly divided into training (n = 1563) and testing (n = 781) data sets. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |
| 12 | CONCLUSIONS: SNPs in BCMO1 are associated with plasma carotenoid concentrations. | Carotenoids | beta-carotene oxygenase 1 | Homo sapiens |