Title : Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo.

Pub. Date : 2013 Mar

PMID : 23121445






2 Functional Relationships(s)
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Protein Name
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1 BACKGROUND: The SH2-containing inositol-5"-phosphatase 1 (SHIP1) metabolizes PI(3,4,5)P3 to PI(3,4)P2. phosphoinositide-3,4,5-triphosphate inositol polyphosphate-5-phosphatase D Homo sapiens
2 BACKGROUND: The SH2-containing inositol-5"-phosphatase 1 (SHIP1) metabolizes PI(3,4,5)P3 to PI(3,4)P2. phosphoinositide-3,4,5-triphosphate inositol polyphosphate-5-phosphatase D Homo sapiens