Title : Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression.

Pub. Date : 2013 Jan 1

PMID : 23103450






3 Functional Relationships(s)
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Protein Name
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1 Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression. Arsenic Trioxide ETS transcription factor ERG Homo sapiens
2 Arsenic trioxide (As(2)O(3)), which is used to treat acute promyelocytic leukemia, can cause LQTS type 2 (LQT2) by reducing the hERG current through the diversion of hERG trafficking to the cytoplasmic membrane. Arsenic Trioxide ETS transcription factor ERG Homo sapiens
3 Arsenic trioxide (As(2)O(3)), which is used to treat acute promyelocytic leukemia, can cause LQTS type 2 (LQT2) by reducing the hERG current through the diversion of hERG trafficking to the cytoplasmic membrane. Arsenic Trioxide ETS transcription factor ERG Homo sapiens