Pub. Date : 2013 Feb
PMID : 23086036
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We determined the effect of IL-6 exposure on glucose and lipid metabolism in cultured myotubes established from people with normal glucose tolerance or type 2 diabetes. | Glucose | interleukin 6 | Homo sapiens |
| 2 | Acute IL-6 exposure increased glycogen synthesis, glucose uptake, and signal transducer and activator of transcription 3 (STAT3) phosphorylation in cultured myotubes from normal glucose tolerant subjects. | Glucose | interleukin 6 | Homo sapiens |
| 3 | Acute IL-6 exposure increased glycogen synthesis, glucose uptake, and signal transducer and activator of transcription 3 (STAT3) phosphorylation in cultured myotubes from normal glucose tolerant subjects. | Glucose | interleukin 6 | Homo sapiens |
| 4 | IL-6 increased fatty acid oxidation in myotubes from type 2 diabetic and normal glucose tolerant subjects. | Glucose | interleukin 6 | Homo sapiens |
| 5 | In summary, skeletal muscle cells from type 2 diabetic patients display selective IL-6 resistance for glucose rather than lipid metabolism. | Glucose | interleukin 6 | Homo sapiens |
| 6 | In conclusion, IL-6 appears to play a differential role in regulating metabolism in type 2 diabetic patients compared with normal glucose tolerant subjects. | Glucose | interleukin 6 | Homo sapiens |