Pub. Date : 2012 Nov 30
PMID : 23085347
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pretreatment with Klotho protein resulted in remarkable increase of cell viability and decrease of ROS production in IS-treated HUVECs. | Reactive Oxygen Species | klotho | Homo sapiens |
| 2 | Like ROS scavenger, N-acetyl-l-cysteine (NAC), Klotho protein could inhibit the IS-induced activations of p38MAPK and NF-kappaB. | Reactive Oxygen Species | klotho | Homo sapiens |
| 3 | Klotho protein has the ability to ameliorate the IS-induced endothelial dysfunction, which may be partly through inhibiting the ROS/p38MAPK and downstream NF-kappaB signaling pathways. | Reactive Oxygen Species | klotho | Homo sapiens |