Title : Lipid A 3'-O-deacylation by Salmonella outer membrane enzyme LpxR modulates the ability of lipid A to stimulate Toll-like receptor 4.

Pub. Date : 2012 Nov 23

PMID : 23085233






3 Functional Relationships(s)
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1 We examined whether lipid A 3"-O-deacylation by Salmonella lipid A deacylase LpxR affected the ability of lipid A to stimulate the Toll-like receptor 4 (TLR4) and MD-2 complex. Lipid A toll like receptor 4 Homo sapiens
2 We examined whether lipid A 3"-O-deacylation by Salmonella lipid A deacylase LpxR affected the ability of lipid A to stimulate the Toll-like receptor 4 (TLR4) and MD-2 complex. Lipid A toll like receptor 4 Homo sapiens
3 An NF-kappaB-dependent reporter activation assay was used to determine the bioactivity of the lipid A species in a cell line that expressed human TLR4 and MD-2 complex. Lipid A toll like receptor 4 Homo sapiens