Pub. Date : 2012 Nov 16
PMID : 23085230
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 5-Fluorocytosine combined with Fcy-hEGF fusion protein targets EGFR-expressing cancer cells. | Flucytosine | epidermal growth factor receptor | Homo sapiens |
| 2 | Here, we adopted a prodrug system that uses 5-fluorocytosine (5-FC) and human EGF (hEGF) fused with yeast cytosine deaminase (Fcy) to target EGFR-overexpressing cancer cells and to convert 5-FC to a significantly more toxic chemotherapeutic, 5-fluorouracil (5-FU). | Flucytosine | epidermal growth factor receptor | Homo sapiens |
| 3 | Here, we adopted a prodrug system that uses 5-fluorocytosine (5-FC) and human EGF (hEGF) fused with yeast cytosine deaminase (Fcy) to target EGFR-overexpressing cancer cells and to convert 5-FC to a significantly more toxic chemotherapeutic, 5-fluorouracil (5-FU). | Flucytosine | epidermal growth factor receptor | Homo sapiens |