Title : New indication for therapeutic potential of an old well-known drug (propranolol) for multiple myeloma.

Pub. Date : 2013 Feb

PMID : 23080133






2 Functional Relationships(s)
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1 METHODS: Time-dependent antiproliferation and apoptotic effects of propranolol were subsequently determined by MTT cell proliferation assay, changes in caspase-3 activity, loss of mitochondrial membrane potential (MMP), and also the localization of phosphatidylserine in the plasma membrane. Propranolol caspase 3 Homo sapiens
2 There were significant increases in caspase-3 activity, loss of MMP, and increases in apoptotic cell population in response to propranolol in U266 cells in a time- and dose-dependent manner. Propranolol caspase 3 Homo sapiens