Title : Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.

Pub. Date : 2012

PMID : 23071439






1 Functional Relationships(s)
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1 Herein, we establish how temperature dependent shifts in the lipid A of Yersinia pestis LPS that differentially impact recognition by mouse versus human TLR4/MD-2 dictate infection susceptibility. Lipid A toll like receptor 4 Homo sapiens