Title : Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.

Pub. Date : 2012 Dec 1

PMID : 23067554






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Recently, we recognized lithocholic acid (LCA) as a natural inhibitor against PTP1B (IC(50)=12.74 muM) by a vertical screen for the first time. Lithocholic Acid latexin Homo sapiens
2 Recently, we recognized lithocholic acid (LCA) as a natural inhibitor against PTP1B (IC(50)=12.74 muM) by a vertical screen for the first time. Lithocholic Acid latexin Homo sapiens