Title : Uptake of silica and carbon nanotubes by human macrophages/monocytes induces activation of fibroblasts in vitro -- potential implication for pathogenesis of inflammation and fibrotic diseases.

Pub. Date : 2012 Jul-Sep

PMID : 23058021






1 Functional Relationships(s)
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1 Silica stimulation showed a significant increase of IL-1alpha and IL-1beta in cultured medium, and an increased gene expression of CTGF in cultured fibroblasts at 1 hour, as well as an up-regulation of the COL1A2 gene at 24-hour time point. Silicon Dioxide interleukin 1 alpha Homo sapiens