Title : Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.

Pub. Date : 2012

PMID : 23050005






1 Functional Relationships(s)
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Protein Name
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1 Although DOCK2 does not contain the Dbl homology domain typically found in guanine nucleotide exchange factors (GEFs), DOCK2 mediates the GTP-GDP exchange reaction for Rac via its DOCK homology region (DHR)-2 (also known as CZH2 or Docker) domain. Guanine Nucleotides AKT serine/threonine kinase 1 Homo sapiens