Title : In vitro oxidative inactivation of human presequence protease (hPreP).

Pub. Date : 2012 Dec 1

PMID : 23041349






1 Functional Relationships(s)
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1 Recent studies showed that PreP activity is reduced in Alzheimer disease (AD) patients and AD mouse models compared to controls, which correlated with an enhanced reactive oxygen species production in mitochondria. Reactive Oxygen Species prolyl endopeptidase Homo sapiens