Title : The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice.

Pub. Date : 2013 Jan

PMID : 23041323






2 Functional Relationships(s)
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1 Application of deoxycholic acid, lithocholic acid, or oleanolic acid (a selective agonist of TGR5) to the mucosa of tgr5-wt mice caused oral contraction and caudal relaxation, indicating peristalsis. Oleanolic Acid G protein-coupled bile acid receptor 1 Mus musculus
2 Application of deoxycholic acid, lithocholic acid, or oleanolic acid (a selective agonist of TGR5) to the mucosa of tgr5-wt mice caused oral contraction and caudal relaxation, indicating peristalsis. Oleanolic Acid G protein-coupled bile acid receptor 1 Mus musculus