Title : Targeting the estrogen receptor using steroid-therapeutic drug conjugates (hybrids).

Pub. Date : 2012 Nov 21

PMID : 23036054






3 Functional Relationships(s)
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1 Targeting the estrogen receptor using steroid-therapeutic drug conjugates (hybrids). Steroids estrogen receptor 1 Homo sapiens
2 In this review, we describe the strategies and methods employed by those investigators in their efforts to develop steroid-drug conjugates with the goals of enhanced antiproliferative activity and ER-selectivity. Steroids estrogen receptor 1 Homo sapiens
3 In particular, the choices of steroid scaffolds and sites for drug conjugation have evolved as the understanding of role of ER in cell function has expanded. Steroids estrogen receptor 1 Homo sapiens