Pub. Date : 2013 Feb
PMID : 23013513
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of simvastatin and ezetimibe on interleukin-6 and high-sensitivity C-reactive protein. | Simvastatin | interleukin 6 | Homo sapiens |
| 2 | Median changes (interquartile range) in IL-6 and hsCRP concentrations were -22% (-43 to 0%) and -30% (-44 to +19%) after simvastatin, -5% (-36 to +30%) and +9% (-22 to +107%) after ezetimibe, and +15% (-15 to +86%) and +1 (-30 to +49%) after the combination. | Simvastatin | interleukin 6 | Homo sapiens |
| 3 | CONCLUSIONS: Simvastatin decreases the pro-inflammatory markers IL-6 and almost significantly hsCRP while ezetimibe monotherapy or the combination with simvastatin has no effect. | Simvastatin | interleukin 6 | Homo sapiens |