Pub. Date : 2012 Dec 7
PMID : 23011394
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PA endothelial cells isolated from Apc(Min/+) demonstrated reduced survival and angiogenic responses along with a profound reduction in adhesion to laminin. | Protactinium | APC regulator of WNT signaling pathway | Homo sapiens |
2 | We found that PA endothelial cells from lungs of patients with idiopathic PH have reduced APC expression, decreased adhesion to laminin, and impaired vascular tube formation. | Protactinium | APC regulator of WNT signaling pathway | Homo sapiens |
3 | CONCLUSIONS: We show that APC is integral to PA endothelial cells adhesion and survival and is reduced in PA endothelial cells from PH patient lungs. | Protactinium | APC regulator of WNT signaling pathway | Homo sapiens |