Pub. Date : 2012 Nov 15
PMID : 23011059
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Reduced arginine availability stemming from reduced de novo production and elevated arginase activity have been reported in various conditions of acute and chronic stress, which are often characterized by increased NOS2 and reduced NOS3 activity. | Arginine | nitric oxide synthase 3 | Homo sapiens |
| 2 | Therapeutic applications to influence (de novo) arginine and NO metabolism aim at increasing substrate availability or at influencing the metabolic fate of specific pathways related to NO bioavailability and prevention of NOS3 uncoupling. | Arginine | nitric oxide synthase 3 | Homo sapiens |