Title : The crucial role of divalent metal ions in the DNA-acting efficacy and inhibition of the transcription of dimeric chromomycin A3.

Pub. Date : 2012

PMID : 22984445






1 Functional Relationships(s)
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1 In the DNA integrity assays, the DNA cleavage rate of Co(II)(Chro)(2) (1.2 x 10(-3) s(-1)) is higher than those of Fe(II)(Chro)(2) and Ni(II)(Chro)(2), which were calculated to be 1 x 10(-4) and 3.1 x 10(-4) s(-1), respectively. ammonium ferrous sulfate mitochondrially encoded cytochrome c oxidase II Homo sapiens